Kulkarni Lab

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Kulkarni Lab August 2025

Maturity-onset diabetes of the young/Monogenic diabetes
Fluorescein-based sensors to purify human a-cells for functional and transcriptomic analyses.
Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid-sensitive hypoglycemia.
NREP contributes to development of NAFLD by regulating one-carbon metabolism in primary human hepatocytes.
Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways.
Monogenic diabetes.

Joslin Diabetes Center
One Joslin Place
Boston, MA 02215
United States