Blackwell Laboratory

2013

Ruf V, Holzem C, Peyman T, Walz G, Blackwell K, Neumann-Haefelin E. TORC2 signaling antagonizes SKN-1 to induce C. elegans mesendodermal embryonic development. Developmental biology. 2013;384(2):214–227.

Paek J, Lo JY, Narasimhan SD, Nguyen TN, Glover-Cutter K, Robida-Stubbs S, Suzuki T, Yamamoto M, Blackwell K, Curran SP. Mitochondrial SKN-1/Nrf mediates a conserved starvation response. Cell metabolism. 2012;16(4):526–537.

Mori MA, Raghavan P, Thomou T, Boucher J, Robida-Stubbs S, Macotela Y, Russell SJ, Kirkland JL, Blackwell K, Kahn R. Role of microRNA processing in adipose tissue in stress defense and longevity. Cell metabolism. 2012;16(3):336–347.

Robida-Stubbs S, Glover-Cutter K, Lamming DW, Mizunuma M, Narasimhan SD, Neumann-Haefelin E, Sabatini DM, Blackwell K. TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO. Cell metabolism. 2012;15(5):713–724.

Li X, Matilainen O, Jin C, Glover-Cutter KM, Holmberg CI, Blackwell K. Specific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activity. PLoS genetics. 2011;7(6):e1002119.

Abate JP, Blackwell K. Life is short, if sweet. Cell metabolism. 2009;10(5):338–339.

Oliveira RP, Abate JP, Dilks K, Landis J, Ashraf J, Murphy CT, Blackwell K. Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf. Aging cell. 2009;8(5):524–541.

Hammell CM, Lubin I, Boag PR, Blackwell K, Ambros V. nhl-2 Modulates microRNA activity in Caenorhabditis elegans. Cell. 2009;136(5):926–938.

Castillo-Quan JI an, Tain LS, Kinghorn KJ, Li L, Grönke S, Hinze Y, Blackwell TK, Bjedov I, Partridge L. A triple drug combination targeting components of the nutrient-sensing network maximizes longevity. Proceedings of the National Academy of Sciences. 2019;116(42):20817–20819.
Wu Z, Isik M, Moroz N, Steinbaugh MJ, Zhang P, Blackwell TK. Dietary restriction extends lifespan through metabolic regulation of innate immunity. Cell metabolism. 2019;29(5):1192–1205.
Blackwell TK, Sewell AK, Wu Z, Han M. TOR Signaling in Caenorhabditis elegans Development, Metabolism, and Aging. Genetics. 2019;213(2):329–360.
Wu Z, Senchuk MM, Dues DJ, Johnson BK, Cooper JF, Lew L, Machiela E, Schaar CE, DeJonge H, Blackwell TK, et al. Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways. BMC biology. 2018;16(1):147.
Ewald CY, Castillo-Quan JI an, Blackwell TK. Untangling longevity, Dauer, and healthspan in Caenorhabditis elegans insulin/IGF-1-signalling. Gerontology. 2018;64(1):96–104.
Ewald CY, Hourihan JM, Bland MS, Obieglo C, Katic I, Mazzeo LEM, Alcedo J, Blackwell TK, Hynes NE. NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans. Elife. 2017;6:e19493.