Publications

Isik M, Blackwell TK, Berezikov E. MicroRNA mir-34 provides robustness to environmental stress response via the DAF-16 network in C. elegans. Scientific reports. 2016;6:36766.

Hourihan JM, Mazzeo LEM, ardenas PF andez-C, Blackwell TK. Cysteine sulfenylation directs IRE-1 to activate the SKN-1/Nrf2 antioxidant response. Molecular cell. 2016;63(4):553–566.

Ogawa T, Kodera Y, Hirata D, Blackwell TK, Mizunuma M. Natural thioallyl compounds increase oxidative stress resistance and lifespan in Caenorhabditis elegans by modulating SKN-1/Nrf. Scientific reports. 2016;6:21611.

Blackwell TK, Steinbaugh MJ, Hourihan JM, Ewald CY, Isik M. SKN-1/Nrf, stress responses, and aging in Caenorhabditis elegans. Free Radical Biology and Medicine. 2015;88:290–301.

Ewald CY, Landis JN, Abate JP, Murphy CT, Blackwell TK. Dauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity. Nature. 2015;519(7541):97.

Steinbaugh MJ, Narasimhan SD, Robida-Stubbs S, Mazzeo LEM, Dreyfuss JM, Hourihan JM, Raghavan P, Operana TN, Esmaillie R, Blackwell TK. Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence. elife. 2015;4:e07836.

Moroz N, Carmona JJ, Anderson E, Hart AC, Sinclair DA, Blackwell TK. Dietary restriction involves NAD+-dependent mechanisms and a shift toward oxidative metabolism. Aging cell. 2014;13(6):1075–1085.

Mizunuma M, Neumann-Haefelin E, Moroz N, Li Y, Blackwell TK. m TORC 2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity. Aging cell. 2014;13(5):869–878.

Yoon JC, Ling AJ, Isik M, Lee D-YD, Steinbaugh MJ, Sack LM, Boduch AN, Blackwell TK, Sinclair DA, Elledge SJ. GLTSCR2/PICT1 links mitochondrial stress and Myc signaling. Proceedings of the National Academy of Sciences. 2014;111(10):3781–3786.

Ishikado A, Sono Y, Matsumoto M, Robida-Stubbs S, Okuno A, Goto M, King GL, Blackwell K, Makino T. Willow bark extract increases antioxidant enzymes and reduces oxidative stress through activation of Nrf2 in vascular endothelial cells and Caenorhabditis elegans. Free Radical Biology and Medicine. 2013;65:1506–1515.