Ng NHJ, Jasmen JB, Lim CS, Lau HH, Krishnan VG, Kadiwala J, Kulkarni RN, R\aeder H, Vallier L, Hoon S, et al. HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells. iScience. 2019;16:192–205.
Publications
2019
Ji Y, Sun S, Shrestha N, Darragh LB, Shirakawa J, Xing Y, He Y, Carboneau BA, Kim H, An D, et al. Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β-cells in diet-induced obesity. Nature immunology. 2019;20(6):677.
Mezza T, Cinti F, Cefalo CMA, Pontecorvi A, Kulkarni RN, Giaccari A. β-Cell Fate in Human Insulin Resistance and Type 2 Diabetes: A Perspective on Islet Plasticity. Diabetes. 2019;68(6):1121–1129.
Dirice E, Kahraman S, De Jesus DF, Ouaamari AE, Basile G, Baker RL, Yigit B, Piehowski PD, Kim M-J, Dwyer AJ, et al. Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes. Nature Metabolism. 2019;1(5):509.
Basile G, Kulkarni RN, Morgan NG. How, When, and Where Do Human β-Cells Regenerate?. Current Diabetes Reports. 2019;19(8):48.
Loo LSW, Vethe H, Soetedjo AAP, Paulo JA, Jasmen J, Jackson N, Bj\orlykke Y, Valdez IA, Vaudel M, Barsnes H, et al. Dynamic Proteome Profiling of Human Pluripotent Stem Cell-Derived Pancreatic Progenitors. Stem Cells. 2019.
Zhang Z, Zhan Q, Eckert M, Zhu A, Chryplewicz A, De Jesus DF, Ren D, Kulkarni RN, Lengyel E, He C, et al. RADAR: Differential Analysis of MeRIP-seq Data With a Random Effect Model. Genome Biology. 2019;20(1):294.
De Jesus DF, Kulkarni RN. "Omics" and "Epi-Omics" Underlying the β-Cell Adaptation to Insulin Resistance. Molecular Metabolism. 2019;27(S):42-48.
De Jesus DF, Zhang Z, Kahraman S, Brown NK, Chen M, Hu J, Gupta MK, He C, Kulkarni RN. M 6 A mRNA Methylation Regulates Human β-Cell Biology in Physiological States and in Type 2 Diabetes. Nature Metabolism. 2019;1(8):765-774.
2018
Gannon M, Kulkarni RN, Hubert T, Mauvais-Jarvis F. Sex differences underlying pancreatic islet biology and its dysfunction. Molecular metabolism. 2018;15:82–91.