Negahdar M, Aukrust I, Molnes J, Solheim MH, Johansson BB, Sagen J V, Dahl-J\orgensen K, Kulkarni RN, S\ovik O, Flatmark T, et al. GCK-MODY diabetes as a protein misfolding disease: the mutation R275C promotes protein misfolding, self-association and cellular degradation. Molecular and cellular endocrinology. 2013;382(1):55–65.
Publications
2013
Koh H-J, Toyoda T, Didesch MM, Lee M-Y, Sleeman MW, Kulkarni RN, Musi N, Hirshman MF, Goodyear LJ. Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle. Nature communications. 2013;4:1871.
R\aeder H, Vesterhus M, Ouaamari AE, Paulo JA, McAllister FE, Liew CW, Hu J, Kawamori D, Molven A, Gygi SP, et al. Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young). PloS one. 2013;8(4):e60229.
Akiyama M, Liew CW, Lu S, Hu J, Martinez R, Hambro B, Kennedy RT, Kulkarni RN. X-box binding protein 1 is essential for insulin regulation of pancreatic $\alpha$-cell function. Diabetes. 2013;62(7):2439–2449.
Mezza T, Muscogiuri G, Sorice GP, Clemente G, Hu J, Pontecorvi A, Holst JJ, Giaccari A, Kulkarni RN. Insulin resistance alters islet morphology in nondiabetic humans. Diabetes. 2013;63(3):994–1007.
Teo AKK, Wagers AJ, Kulkarni RN. New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism. Cell metabolism. 2013;18(6):775–791.
2012
Galkina E V, Butcher M, Keller SR, Goff M, Bruce A, Pei H, Sarembock IJ, Sanders JM, Nagelin MH, Srinivasan S, et al. Accelerated atherosclerosis in Apoe-/- mice heterozygous for the insulin receptor and the insulin receptor substrate-1. Arteriosclerosis, thrombosis, and vascular biology. 2012;32(2):247–256.
Lee EK, Kim W, Tominaga K, Martindale JL, Yang X, Subaran SS, Carlson OD, Mercken EM, Kulkarni RN, Akamatsu W, et al. RNA-binding protein HuD controls insulin translation. Molecular cell. 2012;45(6):826–835.
Halperin F, Lopez X, Manning R, Kahn R, Kulkarni RN, Goldfine AB. Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans. Diabetes. 2012;61(2):301–309.
Morioka T, Dishinger JF, Reid KR, Liew CW, Zhang T, Inaba M, Kennedy RT, Kulkarni RN. Enhanced GLP-1-and sulfonylurea-induced insulin secretion in islets lacking leptin signaling. Molecular Endocrinology. 2012;26(6):967–976.