Kulkarni RN, Stewart AF. Summary of the Keystone islet workshop (April 2014): the increasing demand for human islet availability in diabetes research. 2014.
Publications
2014
2013
Liew CW, Boucher J, Cheong JK, Vernochet C, Koh H-J, Mallol C, Townsend K, Langin D, Kawamori D, Hu J, et al. Ablation of TRIP-Br2, a novel regulator of fat lipolysis, thermogenesis and oxidative metabolism, prevents diet-induced obesity and insulin resistance. Nature medicine. 2013.
Teo AK, Windmueller R, Johansson BB, Dirice E, Njolstad PR, Tjora E, Raeder H, Kulkarni RN. Derivation of human induced pluripotent stem cells from patients with maturity onset diabetes of the young. Journal of Biological Chemistry. 2013;288(8):5353–5356.
Aukrust I, Bj\orkhaug L, Negahdar M, Molnes J, Johansson BB, Müller Y, Haas W, Gygi SP, S\ovik O, Flatmark T, et al. SUMOylation of pancreatic glucokinase regulates its cellular stability and activity. Journal of Biological Chemistry. 2013;288(8):5951–5962.
Ouaamari AE, Kawamori D, Dirice E, Liew CW, Shadrach JL, Hu J, Katsuta H, Hollister-Lock J, Qian W-J, Wagers AJ, et al. Liver-derived systemic factors drive β cell hyperplasia in insulin-resistant states. Cell reports. 2013;3(2):401–410.
Negahdar M, Aukrust I, Molnes J, Solheim MH, Johansson BB, Sagen J V, Dahl-J\orgensen K, Kulkarni RN, S\ovik O, Flatmark T, et al. GCK-MODY diabetes as a protein misfolding disease: the mutation R275C promotes protein misfolding, self-association and cellular degradation. Molecular and cellular endocrinology. 2013;382(1):55–65.
Koh H-J, Toyoda T, Didesch MM, Lee M-Y, Sleeman MW, Kulkarni RN, Musi N, Hirshman MF, Goodyear LJ. Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle. Nature communications. 2013;4:1871.
R\aeder H, Vesterhus M, Ouaamari AE, Paulo JA, McAllister FE, Liew CW, Hu J, Kawamori D, Molven A, Gygi SP, et al. Absence of diabetes and pancreatic exocrine dysfunction in a transgenic model of carboxyl-ester lipase-MODY (maturity-onset diabetes of the young). PloS one. 2013;8(4):e60229.
Akiyama M, Liew CW, Lu S, Hu J, Martinez R, Hambro B, Kennedy RT, Kulkarni RN. X-box binding protein 1 is essential for insulin regulation of pancreatic $\alpha$-cell function. Diabetes. 2013;62(7):2439–2449.
Mezza T, Muscogiuri G, Sorice GP, Clemente G, Hu J, Pontecorvi A, Holst JJ, Giaccari A, Kulkarni RN. Insulin resistance alters islet morphology in nondiabetic humans. Diabetes. 2013;63(3):994–1007.