Flier SN, Kulkarni RN, Kahn R. Evidence for a circulating islet cell growth factor in insulin-resistant states. Proceedings of the National Academy of Sciences. 2001;98(13):7475–7480.
Publications
2001
Leibiger B, Leibiger IB, Moede T, Kemper S, Kulkarni RN, Kahn R, De Vargas LM, Berggren P-O. Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic $\beta$ cells. Molecular cell. 2001;7(3):559–570.
2000
Kulkarni R, Wang Z, Wang R, Smith D, Ghatei M, . Glibenclamide but not other sulphonylureas stimulates release of neuropeptide Y from perifused rat islets and hamster insulinoma cells. Journal of endocrinology. 2000;165(2):509–518.
Mauvais-Jarvis F, Virkamaki A, Michael D, Winnay JN, Zisman A, Kulkarni RN, Kahn R. A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes.. Diabetes. 2000;49(12):2126–2134.
Michael D, Kulkarni RN, Postic C, Previs SF, Shulman GI, Magnuson MA, Kahn R. Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. Molecular cell. 2000;6(1):87–97.
Aspinwall CA, Qian W-J, Roper MG, Kulkarni RN, Kahn R, Kennedy RT. Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta-cells. Journal of Biological Chemistry. 2000;275(29):22331–22338.
Kahn R, Brüning JС, Michael D, Kulkarni RN. Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes mellitus. Journal of Pediatric Endocrinology and Metabolism. 2000;13(Supplement):1377–1384.
1999
Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, Kahn R. Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell. 1999;96(3):329–339.
Kulkarni RN, Winnay JN, Daniels M, Brüning JC, Flier SN, Hanahan D, Kahn R. Altered function of insulin receptor substrate-1–deficient mouse islets and cultured beta-cell lines. The Journal of clinical investigation. 1999;104(12):R69–R75.