Teo AKK, Gupta MK, Doria A, Kulkarni RN. Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools. Molecular metabolism. 2015;4(9):593–604.
Publications
2015
Bhatt S, Gupta MK, Khamaisi M, Martinez R, Gritsenko MA, Wagner BK, Guye P, Busskamp V, Shirakawa J, Wu G, et al. Preserved DNA damage checkpoint pathway protects against complications in long-standing type 1 diabetes. Cell metabolism. 2015;22(2):239–252.
Lee Y-J, Liu C, Liao M, Sukhova GK, Shirakawa J, Abdennour M, Iamarene K, Andre S, Inouye K, Clement K, et al. Deficiency of FcϵR1 Increases Body Weight Gain but Improves Glucose Tolerance in Diet-Induced Obese Mice. Endocrinology. 2015;156(11):4047–4058.
Ghanem SS, Heinrich G, Lester SG, Pfeiffer V, Bhattacharya S, Patel PR, DeAngelis AM, Dai T, Ramakrishnan SK, Smiley ZN, et al. Increased glucose-induced secretion of glucagon-like peptide-1 in mice lacking the carcinoembryonic antigen-related cell adhesion molecule 2 (CEACAM2). Journal of Biological Chemistry. 2015;291(2):980–988.
Gupta MK, Teo AKK, Rao TN, Bhatt S, Kleinridders A, Shirakawa J, Takatani T, Hu J, De Jesus DF, Windmueller R, et al. Excessive cellular proliferation negatively impacts reprogramming efficiency of human fibroblasts. Stem cells translational medicine. 2015;4(10):1101–1108.
Mezza T, Sorice GP, Conte C, Sun VA, Cefalo CM, Moffa S, Pontecorvi A, Mari A, Kulkarni RN, Giaccari A. Beta cell glucose sensitivity is linked to insulin/glucagon bihormonal cells in non-diabetic humans. The Journal of Clinical Endocrinology & Metabolism. 2015;101(2):470–475.
2014
R\aeder H, McAllister FE, Tjora E, Bhatt S, Haldorsen I, Hu J, Willems SM, Vesterhus M, Ouaamari AE, Liu M, et al. Carboxyl-ester lipase maturity-onset diabetes of the young is associated with development of pancreatic cysts and upregulated MAPK signaling in secretin-stimulated duodenal fluid. Diabetes. 2014;63(1):259–269.
Kilic G, Alvarez-Mercado AI, Zarrouki B, Opland D, Liew CW, Alonso LC, Myers MG Jr, Jonas J-C, Poitout V, Kulkarni RN, et al. The Islet Estrogen Receptor-α Is Induced by Hyperglycemia and Protects Against Oxidative Stress-Induced Insulin-Deficient Diabetes. PLoS One. 2014;9(2):e87941.
Winnay JN, Dirice E, Liew CW, Kulkarni RN, Kahn R. p85α deficiency protects β-cells from endoplasmic reticulum stress-induced apoptosis. Proceedings of the National Academy of Sciences. 2014;111(3):1192–1197.
Dirice E, Kahraman S, Jiang W, Ouaamari AE, De Jesus DF, Teo AK, Hu J, Kawamori D, Gaglia JL, Mathis D, et al. Soluble factors secreted by T cells promote β-cell proliferation. Diabetes. 2014;63(1):188–202.