Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways

Wu Z, Senchuk MM, Dues DJ, Johnson BK, Cooper JF, Lew L, Machiela E, Schaar CE, DeJonge H, Blackwell TK, et al. Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways. BMC biology. 2018;16(1):147.

Last updated on 06/19/2020

Recent Publications

Castillo-Quan JI an, Tain LS, Kinghorn KJ, Li L, Grönke S, Hinze Y, Blackwell TK, Bjedov I, Partridge L. A triple drug combination targeting components of the nutrient-sensing network maximizes longevity. Proceedings of the National Academy of Sciences. 2019;116(42):20817–20819.
Wu Z, Isik M, Moroz N, Steinbaugh MJ, Zhang P, Blackwell TK. Dietary restriction extends lifespan through metabolic regulation of innate immunity. Cell metabolism. 2019;29(5):1192–1205.
Blackwell TK, Sewell AK, Wu Z, Han M. TOR Signaling in Caenorhabditis elegans Development, Metabolism, and Aging. Genetics. 2019;213(2):329–360.
Wu Z, Senchuk MM, Dues DJ, Johnson BK, Cooper JF, Lew L, Machiela E, Schaar CE, DeJonge H, Blackwell TK, et al. Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways. BMC biology. 2018;16(1):147.
Ewald CY, Castillo-Quan JI an, Blackwell TK. Untangling longevity, Dauer, and healthspan in Caenorhabditis elegans insulin/IGF-1-signalling. Gerontology. 2018;64(1):96–104.
Ewald CY, Hourihan JM, Bland MS, Obieglo C, Katic I, Mazzeo LEM, Alcedo J, Blackwell TK, Hynes NE. NADPH oxidase-mediated redox signaling promotes oxidative stress resistance and longevity through memo-1 in C. elegans. Elife. 2017;6:e19493.

Publication by Year

2019 (3)
2018 (2)
2017 (4)
2016 (4)
2015 (3)
2014 (3)
2013 (3)
2012 (3)
2011 (1)
2010 (1)