Kulkarni RN, Zisman A. Lessons for human diabetes from experimental mouse models. Current diabetes reports. 2003;3(2):168–175.
Publications
2003
Du K, Herzig S, Kulkarni RN, Montminy M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science. 2003;300(5625):1574–1577.
Hennige AM, Burks DJ, Ozcan U, Kulkarni RN, Ye J, Park S, Schubert M, Fisher TL, Dow MA, Leshan R, et al. Upregulation of insulin receptor substrate-2 in pancreatic $\beta$ cells prevents diabetes. The Journal of clinical investigation. 2003;112(10):1521–1532.
Jhala US, Canettieri G, Screaton RA, Kulkarni RN, Krajewski S, Reed J, Walker J, Lin X, White M, Montminy M. cAMP promotes pancreatic $\beta$-cell survival via CREB-mediated induction of IRS2. Genes & development. 2003;17(13):1575–1580.
Jiang ZY, He Z, King BL, Kuroki T, Opland DM, Suzuma K, Suzuma I, Ueki K, Kulkarni RN, Kahn R, et al. Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis. Journal of Biological Chemistry. 2003;278(34):31964–31971.
Almind K, Kulkarni RN, Lannon SM, Kahn R. Identification of interactive loci linked to insulin and leptin in mice with genetic insulin resistance. Diabetes. 2003;52(6):1535–1543.
2002
Roper MG, Qian W-J, Zhang BB, Kulkarni RN, Kahn R, Kennedy RT. Effect of the insulin mimetic L-783,281 on intracellular [Ca2+] and insulin secretion from pancreatic $\beta$-cells. Diabetes. 2002;51(suppl 1):S43–S49.
Laustsen PG, Michael D, Crute BE, Cohen SE, Ueki K, Kulkarni RN, Keller SR, Lienhard GE, Kahn R. Lipoatrophic diabetes in Irs1-/-/Irs3-/- double knockout mice. Genes & development. 2002;16(24):3213–3222.
Mauvais-Jarvis F, Kulkarni RN, Kahn R. Knockout models are useful tools to dissect the pathophysiology and genetics of insulin resistance. Clinical endocrinology. 2002;57(1):1–9.