Morioka T, Kulkarni RN. Pancreatic islet b-cell failure in obesity. Metabolic Basis of Obesity. 2011:199.
Publications
2011
Spiegel AM, Carter-Su C, Taylor SI, Kulkarni RN. Mechanism of action of hormones that act at the cell surface. In: Williams textbook of endocrinology. Elsevier; 2011. pp. 62–82.
Folli F, Okada T, Perego C, Gunton J, Liew CW, Akiyama M, D\textquoterightAmico A, La Rosa S, Placidi C, Lupi R, et al. Altered insulin receptor signalling and $\beta$-cell cycle dynamics in type 2 diabetes mellitus. PLoS One. 2011;6(11):e28050.
Rowland KJ, Trivedi S, Lee D, Wan K, Kulkarni RN, Holzenberger M, Brubaker PL. Loss of glucagon-like peptide-2–induced proliferation following intestinal epithelial insulin-like growth factor-1–receptor deletion. Gastroenterology. 2011;141(6):2166–2175.
Lopez X, Cypess A, Manning R, O\textquoterightShea S, Kulkarni RN, Goldfine AB. Exogenous insulin enhances glucose-stimulated insulin response in healthy humans independent of changes in free fatty acids. The Journal of Clinical Endocrinology & Metabolism. 2011;96(12):3811–3821.
Dirice E, Kulkarni RN. Pathways regulating b-cell regeneration in type 1, type 2 and gestational diabetes. Islet Cell Growth Factors. 2011:1–15.
2010
Zhang Z, Liew CW, Handy DE, Zhang Y, Leopold JA, Hu J, Guo L, Kulkarni RN, Loscalzo J, Stanton RC. High glucose inhibits glucose-6-phosphate dehydrogenase leading to increased oxidative stress and beta cell apoptosis. The FASEB Journal. 2010;24(5):1497–1505.
Georgia S, Hinault C, Kawamori D, Hu J, Meyer J, Kanji M, Bhushan A, Kulkarni RN. Cyclin D2 is essential for the compensatory $\beta$-cell hyperplastic response to insulin resistance in rodents. Diabetes. 2010;59(4):987–996.
Robertson S, Ishida-Takahashi R, Tawara I, Hu J, Patterson CM, Jones JC, Kulkarni RN, Myers MG. Insufficiency of janus kinase 2–autonomous leptin receptor signals for most physiologic leptin actions. Diabetes. 2010;59(4):782–790.
Cornu M, Modi H, Kawamori D, Kulkarni RN, Joffraud M, Thorens B. Glucagon-like peptide-1 (GLP-1) increases beta-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor (IGF-1R) expression. Journal of Biological Chemistry. 2010;285(14):10538–10545.