Ji Y, Sun S, Shrestha N, Darragh LB, Shirakawa J, Xing Y, He Y, Carboneau BA, Kim H, An D, et al. Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β-cells in diet-induced obesity. Nature immunology. 2019;20(6):677.
Publications
2019
Mezza T, Cinti F, Cefalo CMA, Pontecorvi A, Kulkarni RN, Giaccari A. β-Cell Fate in Human Insulin Resistance and Type 2 Diabetes: A Perspective on Islet Plasticity. Diabetes. 2019;68(6):1121–1129.
Dirice E, Kahraman S, De Jesus DF, Ouaamari AE, Basile G, Baker RL, Yigit B, Piehowski PD, Kim M-J, Dwyer AJ, et al. Increased β-cell proliferation before immune cell invasion prevents progression of type 1 diabetes. Nature Metabolism. 2019;1(5):509.
Basile G, Kulkarni RN, Morgan NG. How, When, and Where Do Human β-Cells Regenerate?. Current Diabetes Reports. 2019;19(8):48.
Loo LSW, Vethe H, Soetedjo AAP, Paulo JA, Jasmen J, Jackson N, Bj\orlykke Y, Valdez IA, Vaudel M, Barsnes H, et al. Dynamic Proteome Profiling of Human Pluripotent Stem Cell-Derived Pancreatic Progenitors. Stem Cells. 2019.
Zhang Z, Zhan Q, Eckert M, Zhu A, Chryplewicz A, De Jesus DF, Ren D, Kulkarni RN, Lengyel E, He C, et al. RADAR: Differential Analysis of MeRIP-seq Data With a Random Effect Model. Genome Biology. 2019;20(1):294.
De Jesus DF, Kulkarni RN. "Omics" and "Epi-Omics" Underlying the β-Cell Adaptation to Insulin Resistance. Molecular Metabolism. 2019;27(S):42–48.
De Jesus DF, Zhang Z, Kahraman S, Brown NK, Chen M, Hu J, Gupta MK, He C, Kulkarni RN. M 6 A mRNA Methylation Regulates Human β-Cell Biology in Physiological States and in Type 2 Diabetes. Nature Metabolism. 2019;1(8):765–774.
2018
Gannon M, Kulkarni RN, Hubert T, Mauvais-Jarvis F. Sex differences underlying pancreatic islet biology and its dysfunction. Molecular metabolism. 2018;15:82–91.
Inoue H, Shirakawa J, Togashi Y, Tajima K, Okuyama T, Kyohara M, Tanaka Y, Orime K, Saisho Y, Yamada T, et al. Signaling between pancreatic β cells and macrophages via S100 calcium-binding protein A8 exacerbates β-cell apoptosis and islet inflammation. Journal of Biological Chemistry. 2018;293(16):5934–5946.