Goren J, Kulkarni RN, Kahn R. Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1. Endocrinology. 2004;145(7):3307–3323.

Kulkarni RN, Roper MG, Dahlgren G, Shih DQ, Kauri LM, Peters JL, Stoffel M, Kennedy RT. Islet secretory defect in insulin receptor substrate 1 null mice is linked with reduced calcium signaling and expression of sarco (endo) plasmic reticulum Ca2+-ATPase (SERCA)-2b and-3. Diabetes. 2004;53(6):1517–1525.

Kulkarni RN, Jhala US, Winnay JN, Krajewski S, Montminy M, Kahn R. PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance. The Journal of clinical investigation. 2004;114(6):828–836.

Otani K, Kulkarni RN, Baldwin AC, Krutzfeldt J, Ueki K, Stoffel M, Kahn R, Polonsky KS. Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice. American journal of physiology-endocrinology and metabolism. 2004;286(1):E41–E49.

Kulkarni RN. The islet beta-cell. Int J Biochem Cell Biol. 2004;36:365–371.

Kulkarni RN, Kahn R. HNFs–linking the liver and pancreatic islets in diabetes. Science. 2004;303(5662):1311–1312.

Rosen ED, Kulkarni RN, Sarraf P, Ozcan U, Okada T, Hsu C-H, Eisenman D, Magnuson MA, Gonzalez FJ, Kahn R, et al. Targeted elimination of peroxisome proliferator-activated receptor $\gamma$ in $\beta$ cells leads to abnormalities in islet mass without compromising glucose homeostasis. Molecular and cellular biology. 2003;23(20):7222–7229.

Kulkarni RN, Almind K, Goren J, Winnay JN, Ueki K, Okada T, Kahn R. Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice. Diabetes. 2003;52(6):1528–1534.

Kulkarni RN, Zisman A. Lessons for human diabetes from experimental mouse models. Current diabetes reports. 2003;3(2):168–175.

Du K, Herzig S, Kulkarni RN, Montminy M. TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science. 2003;300(5625):1574–1577.